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针刺合谷穴对脑功能成像的研究 被引量:22

Effects of acupuncturing of LI4(Hegu) on functional brain imaging
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摘要 目的研究针刺合谷穴引起的脑功能的即刻效应和后效应(时间变化规律)。方法用改进时间簇分析(modified temporal cluster analysis,MTCA)方法对12名健康志愿者针刺合谷穴功能磁共振成像(fMRl)的数据进行处理,得到针刺后脑功能变化的时间和趋势。结果针刺合谷穴在进针后7~9s和拔针后高峰后,还会不规律出现一些小的高峰。结论针刺合谷穴对中枢神经系统影响具有时间特性。 Objective To explore instant and latent cerebral effects (time-associated features) that are induced by acupuncturing of acupoint LI4(Hegu). Methods MTCA(modified temporal cluster analysis) was employed to process the fMRI(functional magnetic resonance imaging) data collected from 12 healthy volunteers subject to acupuncturing of LI4 (Hegu). Features of brain function associated with time and trend responding to acupuncture were obtained. Results Acupuncturing of LI4 caused peaks at 7-9s after pricking in and withdrawal, and small peaks ensued randomly as well. Conclusion Acupuncturing of LI4 (Hegu) effects central nervous system, displaying time-associated features.
出处 《中国CT和MRI杂志》 2005年第2期1-3,共3页 Chinese Journal of CT and MRI
基金 国家自然科学基金资助项目(批准号:90209030)
关键词 合谷穴 针刺 脑功能成像 健康志愿者 即刻效应 FMR1 拔针后 进针 功能磁共振成像 中枢神经系统 functional magnetic resonance imaging, modified temporal cluster analysis acupoint Hegu (LI4)
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参考文献4

  • 1[1]Liu Y,Gao JH,Liu HL,et al.The temporal response of the brain after eating revealed by functional MRI. Nature, 2000,405(6790):1058~1062.
  • 2[2]Yee SH,Gao JH.Improved detection of time windows of brain responses in fMRI using modified temporal clustering analysis. Magnetic Resonance Imaging, 2002,20: 17~26.
  • 3[3]Hui KKS,Liu J, Makris N,et al. Acupuncture modulates the limbic system and subcortical gray structures of the human brain:evidence from fMRI studies in normal subjects. Hum Brain Mapping, 2000,9: 13~25.
  • 4[4]Wu MT,Hsieh JC,Xiong H,et al. Central nervous pathway for acupuncture stimulation :localization of processing with functional MR imaging of the brain-Preliminary experience.Radiology, 1999,212: 133~141.

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