表面麻醉在化学剥脱术治疗雀斑中的应用

Application of surface anesthesia in treating freckle with chemical peeling

目的:研究表面麻醉能否有效地减轻化学剥脱术在治疗雀斑中的疼痛。方法:采用随机对照的方法,将60例雀斑患者随机分为A、B两组。B组术前用利多卡因及654-2的混合液纱布覆盖面部并用塑料薄膜封包30min,术中用改进的视觉模拟评分法进行疼痛评估,术后对皮肤过敏、色素沉着等情况进行比较。结果:疼痛评分,A组:良13例,可16例,差1例;B组优14例,良16例。疼痛值比较两组有显著差异(P<0.01)。术后过敏阳性对比两组无明显差异(P>0.05)。术后6个月色素沉着无可见差异。结论:利多卡因及654-2混合液进行表面麻醉能有效减轻化学剥脱术在治疗雀斑中的疼痛。

Objective Study on whether surface anesthesia can relieve pain caused by chemical peeling. Methods Randomized and control method was employed in the study. Sixty freckle patients were randomly divided into A and B groups with 30 in each group. The patients' faces in group B were covered with lidocaine-654-2 gauze and enveloped with plastic film for 30 minutes before operation. Pain was estimated in the operation using visual analogue scale(VAS). Skin allergy and pigmentation were also compared between the two groups. Results Pain grade in group A showed 13 good, 16 mediocre and 1 disappointing. Pain grade in group B showed 14 excellent, 16 good. There was significant difference in pain score between the two groups (P<0.01). There was no significant difference in post operation skin allergy between the two groups and no visible difference in pigmentation at sixth months post operation. Conclusion Lidocaine-654-2 surface anesthesia can relieve the pain caused by chemical peeling.