双歧杆菌强化的肠内营养支持在胃癌术后早期的应用

The use of bifidobacterium-supplemented enternal nutrient in early postoperative patients with advanced gastric cancer

目的:研究双歧杆菌强化的肠内营养在胃癌术后的早期应用。 方法:选择 60例进展期胃癌病人,随机分为两组,即强化肠内营养组和对照组,每组各 30例。强化肠内营养组于手术后第 1天开始应用能全力加双歧杆菌活菌制剂,共 7天;对照组单用能全力。两组病人分别于手术前 1天和手术后第 7天测定粪便中分泌型IgA,并比较两组感染并发症的发生率。 结果:术后第 7天,强化肠内营养组粪便中分泌型IgA量较对照组明显升高,感染等并发症下降,差异有显著意义性意义(P<0. 05)。 结论:胃癌术后早期应用双歧杆菌强化的肠内营养可改善肠黏膜屏障功能,减少感染性并发症的发生率。

Objective: To study the effect of bifidobacterium-supplemented enteral nutrition in early postoperative patients with gastric cancer. Methods: 60 patients with gastric cancer were divided into two groups: bifidobacterium-supplemented enteral nutrition(BSEN-group, 30 cases), popular enteral nutrition group(EN-group,30 cases). The patients were infused with Nutrison Fibre or bifidobacterium-supplemented Nutrison Fibre for 7 postoperative days. Results: Bifidobacterium-supplemented enteral nutrient was well tolerated. The incidence of infections was significantly lower (P = 0.01) in BSEN-group than in EN-group. Conclusion: Early postoperative enteral nutrition plus bifidobacterium can reduce the rate of postoperative infections in comparison with popular enteral nutrition.