摘要
目的探讨三明治法对晚期肺癌的近期疗效。方法45例患者接受此种治疗。介入法采用Seldinger法化疗药物灌注,每次灌注表阿霉素30mg、卡铂300mg、5-Fu750mg;3D-CRT采用6MV X线,Topslane ARTP系统,总剂量为30～40Gy/10次/2周。介入治疗、3D-CRT、再介入治疗,“夹心”进行。结果45例病人总有效率(CR+PR)为93.3%(42/45),平均生存期为15.5个月。结论采用介入化疗与3D-CRT相结合,可使肺癌的瘤体迅速缩小,生存期延长,生活质量提高,为晚期肺癌有效的治疗手段。
Objective To observe the recently therapeutic effect of the sandwich treatment to the later lung tumor. Methods 45 cases of late lung tumor were given interventional chemotherapy with percutaneous artery ( supplying tumor ) catherized into chemotherapy drugs: pharmorubincin 30mg,carboplatin 300mg,5-Fu 750mg;3D-CRT of DT30-40Gy/10f/2w( with x-ray of 6MV and Topslane ARTP system) was given. Sandwich treatment of interventional chemotherapy ,3D-CRT and interventional chemotherapy was given .Results The effective rate was 93.3% (42/45),the average survival period was 15.5 months. Conclusion Combined therapy of interventional chemotherapy and 3D-CRT can reduce lung tumor quickly. So it has longer survival time, improving survival quality. It was an effective treatment method to the late lung tumor.
关键词
三明治法
晚期肺癌
药物灌注
卡铂
5-FU
化学治疗
late lung tumor
3-dimensional conformal radiation therapy( 3D-CRT)
Interventional chemotherapy
Sandwich treatment
