血型与神经系统疾病关系的研究

Study on relationship between blood type and nervous system diseases

目的 对神经系统疾病患者进行血型分析,研究血型这一遗传因素与神经系统疾病之间的关系。方法 用A、B标准血清玻片法对患有神经系统12种疾病的1 083例患者进行血型测定,并与正常人群 A、B、O血型分布构成比(对照组)进行比较,用卡方(χ2)检验进行统计学处理。结果 1 083例患者中,多发性神经炎、急性脊髓炎、周期性瘫痪3种疾病男性A型血居多;三叉神经痛、格林巴利综合征两种疾病男性B型血居多;病毒性脑炎的男性、多发性硬化的女性、癫痫和重症肌无力的女性 O型血居多,其 A、B、O 血型构成比与正常人比较差异有统计学意义(P <0.05、<0.01),提示 A、B、O血型的人易患上述疾病。结论 12种神经系统疾病分别与 A、B、O血型之间存在一定的关系,不同的血型患神经系统疾病的倾向性不同。

Objective The analysis of the blood type was done on the patients with nervous system diseases for clues in the research of the pathogenic factors-genetic factor. Methods Blood types of 1 083 patients with 12 kinds of neurological diseases were determined by A/S standard serum glassine method, and the results were compared with blood type distribution of normal people. Besides. All the data were treated by χ2 test. Results Among 1 083 patients, polyneuritis, acute myelitis, periodic paralysis men with A blood type; trigminal neuralgia, Guillian-Barre syndrome were more of ten in men with B blood type;virus meningitis, women with sclerosis, epilepsy, myasthenia gravis,were more of ten in women with O blood type. The A, B, O blood type component proportions of the diseases mentioned above and those of the normal people have statistic differences. This presents that people with A, B, or O blood type are easy to catch those diseases. Conclusion Twelve kinds of nervous system diseases respectively relates to A,B,or O blood type in some degree,however different blood types have diferent predominances in different nervous system diseases.