高敏C反应蛋白检测在脑血管疾病中的意义

Clinical significance of hight sensitivity C-reactive protein in patients with cerebrovascular disease

目的:探讨血清高敏C反应蛋白(hight-sensitive C-reactive protein,hs-C R P)与脑血管疾病的关系。方法:采用免疫散射速率比浊法,检测60例脑血管疾病患者和25例健康体检对照者血清hs-C R P水平。结果:18例短暂脑缺血发作(TIA)组hs-C R P为(1.94±1.40)m g/L,25例脑梗死组为(15.51±6.91)m g/L,17例脑出血组为(11.95±4.88)m g/L,20例正常对照组为(1.09±0.66)m g/L,脑梗死组、脑出血组与对照组比较血清hs-C R P水平升高,差异均具有显著性(P<0.001);TIA组与对照组比较差异无显著性(P>0.05)。结论:血清hs-C R P水平与脑血管疾病密切相关,可预测脑血管疾病的危险性,并可作为监测病情和预后判断的指标。

Objective To evaluate the significance of high sensitive C reactive protein (hs CRP) in patients with cerebrovascular disease. Methods The study groups included 18 cases of transient ishemic attack(TIA),25 cases of cerebral thrombosis,17 cases of cerebral hemorrhage,and the control group of 25 healthy subjects. Hs CRP level of each group was measured by immunity rate nephelometry. Results There were significant differences between the levels of serum hs CRP in the patients with cerebral thrombosis,cerebral hemorrhage and control group (P< 0.001). Conclusions The measurement hs CRP will be helpful for the diagnosis cerebral vessel diseases. By continous observation with hs CRP could predict the development of disease.