41株脑膜败血黄杆菌的临床分布及耐药情况

Clinical distribution and resistance of 41 strains of flavobacterium meningosepticum

目的了解该院脑膜败血黄杆菌的临床分布及耐药性。方法常规细菌培养方法,细菌鉴定采用法国生物梅里埃鉴定系统,药敏试验采用琼脂纸片扩散法。结果脑膜败血黄杆菌的临床分布以病房为主,其中ICU病房分布最多,其次是神经外科病房,该菌常存在于患者的痰及脑脊液标本中,且耐药现象较为严重,对含酶抑制剂复合制剂及喹诺酮类药物敏感率较高。结论脑膜败血黄杆菌存在多重耐药现象,动态监测其临床分布及耐药特点,控制其在医院内的传播十分必要。

To learn about clinical distribution and resistance of Flavobacterium meningosepticum. Routine bacteria culture. Bacteria identification adopted France BioMerieux identification system. Susceptibility test adopted Kirby-bauer method. Flavobacterium meningosepticum mainly distributed at ward,especially at ICU ward. Then was Neurosurgery ward. Flavobacterium meningosepticum was often examinated from sputum and cerebrospinal fluid. The multi-drug resistance of flavobacterium meningosepticum was serious. The antibiotic drugs which have higher susceptibility ratio were β-lactam/β-lactamase inhibitor combinations and fluoroquinolones. It′s necessary to observe clinical distribution and resistance of flavobacterium meningosepticum so as to control its spread in hospital.