1William M. Pardridge, Non- invasive drug delivery to the human brain using endogenous blood - brain barrier transport systems [J] .Pharmsei & teeh today, 1999, 2 (2): 49.
2Mathison S, Nagilla R, Kompella UB. Nasal route for direct delivery of solutes to the central nervous system: fact or fiction? [J] .J Drug Targeting, 1998, 5 (6): 415.
4Mygind N & Dahl R, Anatomy, physiology and function of the nasal cavities in health and disease [J] .Advanced Drug Delivery Reviews 1998, 29 (12): 3.
5Perlman S, Barnett E M et al. Mouse hepatitis virus and herpes simplex virus move almag different CNS pathways [J] . Adv.Exp.Med.Biol., 1993, 342, 313.
6Ped D P and Good P F Uptake of aluminum into central nervoas system along nasal- olfactory pathways [J] . Lancet, 1987, ( 1 ),1028.
7Hastings L and Evans J Olfactory neuron as a route of entry for toxic agents into the CNS [J] . Neurotoxicol, 1991, 12:707.
8Henriksson J, Tallkvist J, et al. Uptake of nickel into the brain via olfactory netrronsin rats [J]. Toxicol.Lett., 1997, 91:153.
9Anand Kumar T C , David G F X, et al.Uptake of radioactivity by boby fluids and tissues in daesus monkeys aster intravenous injection or intranasal spray of tritium - labeled estradiol and progesterone [J] . Curr. Sci., 1974, 43:435.
10Main M, Anne L, Jean M, et al. Drag transport into the mammalian brain: the nasal pathway and its specific metabolic barrier [J] . J Drug Targeting, 2002, 10 (4) : 285.
