精神分裂症的分子遗传学初探

Preliminary Study of Molecular Genetics of Schizophrenia

本文用4种限制性内切酶（PvuⅡ、PstⅠ、BglⅡ、RsaⅠ）和H-ras－1基因探针分析了40例精神分裂症患者（男女各半）和40例正常者（男女各半）的基因组DNA中H-ras-1基因的RFLP，结果提示，精神分裂症基因不与11号染色体短臂的H-ras-1基因连锁．

This article reports genomic Hrartl gene's KFLP of 40 Schizophrenia patients (20 males, 20females) and 40 unrelated normal controls (20 males, 20 females). Four restriction endonucleases (PvuⅡ,Pst Ⅰ, BglⅡ, Rsa Ⅰ and H-ras-l gtne probe were used to analyse the genome DNA. The preliminarystudy toints out that no evidence of linkage between schizophrenia and H-ras-l gene region onchromosome 11 was found.