摘要
本文用4种限制性内切酶(PvuⅡ、PstⅠ、BglⅡ、RsaⅠ)和H-ras-1基因探针分析了40例精神分裂症患者(男女各半)和40例正常者(男女各半)的基因组DNA中H-ras-1基因的RFLP,结果提示,精神分裂症基因不与11号染色体短臂的H-ras-1基因连锁.
This article reports genomic Hrartl gene's KFLP of 40 Schizophrenia patients (20 males, 20females) and 40 unrelated normal controls (20 males, 20 females). Four restriction endonucleases (PvuⅡ,Pst Ⅰ, BglⅡ, Rsa Ⅰ and H-ras-l gtne probe were used to analyse the genome DNA. The preliminarystudy toints out that no evidence of linkage between schizophrenia and H-ras-l gene region onchromosome 11 was found.
出处
《遗传》
CAS
CSCD
北大核心
1994年第5期14-16,共3页
Hereditas(Beijing)
关键词
精神分裂症
RFLP
分子遗传学
Schizophrenia, Southern blotting, Restriction Fragment Length Polymophisms(RFLP)