中药助孕方加克罗米酚治疗耐克罗米酚的多囊卵巢综合征不孕

Resistant clomiphene sterility with polycystic ovarian syndrome treated by prescription of Chinese traditional medicine benefiting to gravidity and clomiphene

目的:探讨中药助孕方加克罗米酚(CC)治疗常规CC疗法不敏感的多囊卵巢综合征(PCOS)不孕患者的疗效。方法:选择耐CC的PCOS患者68例,随机分成A组和B组。A组:34例患者中药助孕方加CC治疗。B组:34例患者TMX加CC治疗。结果:A组的妊娠明显高于B组(P<0 .05),两组的排卵率、自然流产率比较无显著性差异(P>0 .05)。A组的黄体功能不足及未破裂卵泡发生率明显低于B组。结论:采用中药助孕方联合CC的促排卵方案治疗耐CC的PCOS不孕患者是安全、有效的,具有临床应用和进一步研究的价值。

Objective:To explore the therapeutic effect of prescription of Chinese traditional medicine benefiting to gravidity and clomiphene on patients with resistant clomiphene sterility with polycystic ovarian syndrome (PCOS).Methods:68 patients with resistant clomiphene PCOS were randomly divided into group A (34 cases treated by the prescription and clomiphene) and group B (34 cases treated by tamoxifen and clomiphene).Results: The pregnant rate in group A was significantly higher than that in group B ( P <0.05), there were no significant difference in ovulatory rate and spontaneous abortion rate between two groups ( P >0.05). Inadequate luteal function and incidence of un-rupture ovarian follicle were significantly lower than those of group B.Conclusion:Scheme of promoting ovulation with Chinese traditional medicine benefiting to gravidity combining clomiphene could safely and effectively treat patients with resistant clomiphene PCOS, which has the value of clinical application and further study.