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脊髓损伤的基因治疗实验研究(综述) 被引量：1

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摘要 脊髓是许多神经发挥作用的中介通路.脊髓损伤(SpinalCord Injury,SCI)及其继发的病理生理效应可直接导致神经功能的丧失,造成组织器官功能的障碍,因而具有相当高的致残率和死亡率.到目前为止,虽然修复人类损伤脊髓的目标仍然是一个非常棘手的难题,但自1990年美国国立卫生研究院(NIH)首次成功地进行腺苷脱胺酶缺乏的基因治疗以来,基因治疗已成为当前生物医学中进展最快的领域之一;而且基因治疗在脊髓损伤的动物实验研究中也取得了许多令人鼓舞的进展,为脊髓损伤的修复带来了新的希望.现就近年来对脊髓损伤治疗的基因治疗方法及研究进展作如下综述:
作者 蔡培强 汤逊 林月秋
机构地区 成都军区昆明总医院骨科
出处 《伤残医学杂志》 2005年第1期60-62,共3页 Medical Journal of Trauma and Disability
关键词 脊髓损伤 基因治疗 实验研究 腺苷脱胺酶缺乏
分类号 R651.2 [医药卫生—外科学]
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参考文献22

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同被引文献7

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伤残医学杂志
2005年 第1期

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