垂体后叶素的心血管不良反应临床观察

Clinical Observation of Side-effects of Pituitrin in Cardiovascular System

目的:探讨分析垂体后叶素治疗肝硬化并上消化道出血心血管系统的不良反应。方法:回顾性分析75例肝硬化上消化道出血患者应用垂体后叶素所出现的各种心血管不良反应,并与 20 例应用思他宁的患者作比较。结果:垂休后叶素组发生心血管不良反应的比例明显高于思他宁组,但在肝功能不同分级间无明显差异。结论:常用剂量应用垂体后叶素心血管不良反应发生率高,但无严重不良反应。

Objective: to explore the side-effects of Pituitrin in treatment of liver cirrhosis combined with upper gastrointestinal hemorrhage. Method: Various side –effects in cardiovascular system were retrospectively analyzed in patients with cirrhosis combined with upper gastrointestinal hemorrhage who were treated with Pituitrin , comparison was performed with 20 mimic patients treated with Somatostatin. Result: The proportion of side-effects on cardiovascular system in Pituitrin group is higher than those of Somatostatin group, but significant differences can’t be found in different gradient of liver function. Conclusion: The incidence of side-effect of Pituitrin on cardiovascular system is pretty high but fetal side-effect can’t be observed.