退黄灌肠液治疗肝胆湿热型重度慢性乙型肝炎的临床研究

Clinical Study on Tuihuang Guanchang Ye in Treating Severe Chronic Hepatitis B of Dampness and Heat in the Live and the Gallbladder Type

目的 :观察退黄灌肠液治疗重度慢性乙型肝炎 (肝胆湿热型 )的临床疗效。方法 :三组均在常规支持疗法的基础上 ,对照组口服退黄口服液 ;观察 1组用退黄灌肠液行高位保留灌肠 ;观察 2组用退黄口服液及退黄灌肠液。三组均连续治疗 6 0天 ,统计疗效。结果 :经统计学处理 ,治疗后观察 2组、观察 1组与对照组有效率分别为 90 .0 0 %、6 0 .0 0 %、5 6 .6 7%,在症状、体征、肝功能、PTA及HBVDNA、HBeAg阴转方面的改善 ,观察 2组明显优于观察 1组及对照组 (P <0 .0 5 )。结论 :退黄灌肠液治疗重度慢性乙型肝炎 (肝胆湿热型 )具有良好疗效。

Objective: To observe the clinical effectiveness of Tuihuang Guanchang Ye in treating severe chronic hepatitis B. Method: On the basis of routine therapy, the controlled group took Tuihuang Oral Liquid, the observation group one were given preserved high enema, the observation group two were given Tuihuang Oral Liquid and Tuihuang Guanchang Ye. The therapeutic effectiveness of three groups was counted after 60 days' treatment. Results: According to the statistical analysis, the observation group two, the observation group one and the controlled group had the respective effectiveness rates of 90.00%, 60.00% and 56.67%. In the improvement of the symptorns, signs, liver function, PTA and the negative transmission of HBV-DNA, HBeAg, the observation group two is obviously superior to the observation group one and the controlled group ( P<0.05). Conclusion: Tuihuang Guanchang Ye has a much better therapeutic effectiveness in treating severe chronic hepatitis B (the dampness and heat in the liver and gallbladder type).