糖耐量低减的老年非ST段抬高急性冠状动脉综合征临床分析

Clinical analysis on acute coronary syndrome withont ST-segment elevation in the aged with impaired glucose tolerance

目的:探讨糖耐量低减(IGT)的老年急性冠状动脉综合征(ACS)非ST段抬高病人临床特点。方法:96例ACS患者根据血糖和口服葡萄糖耐量试验(OGTT)被分为:糖尿病(DM)组(32例).糖耐量减低(IGT)组(32例)和糖耐量正常(NGT)组(32例)。所有病人检测血糖,血脂,心电图和作冠状动脉(冠脉)造影,并进行各组间相互比较。结果:DM组和IGT组的血糖、甘油三酯水平比NGT组高(P<0.05～<0.01),而。DM组的血糖水平比IGT组升高更为明显(P<0.05～<0.01)。DM组和IGT组的心电图缺血和冠状动脉造影显示的狭窄比NGT 组重。P<0.01。结论:IGT组和DM组的血脂代谢异常,心肌缺血和血管狭窄程度均明显较NGT组重。故对IGT 的老年病人应警惕冠心病病变。

Objective:To explore the clinical features of acute coronary syndrome (ACS) without ST-segrnent elevation in the aged with impaired glucose tolerance (IGT). Methods:Depending on blood glucose and oral glucose tqlerance test (OGTT), 96 aged ACS patients without ST-segment elevation were assigned to three groups:diabetes mellitus (DM) group (32 cases) , impaired glucose tolerance (IGT) groups (32 cases) , normal glucose tolerance (NGT) group (32 cases). All patients had coronary angiography (CAG) examined. Results:The levels of blood glucose and trigly- ceride (TG) in DM group and IGT group were higher than those in NGT group (P<0.05-<0.01) ;The blood glucose level in DM group more increased than those in IGT group (P<0. 05-<0. 01). The extents of myocardial ischemia of electrocardiogram and the coronary stenosis showed by CAG in DM group and IGT group were more severe than those in NGT group (P<0. 01). Conclusion: The levels of blood glucose and TG, severe extents of myocardial ischemia and coronary artery stenosis in IGT group and DM group increased compared with those of NGT group, so must pay attention to coronary artery disease for the aged with IGT.