猪碘缺乏病（地方性甲状腺肿）的病理学研究

Researches on the Pathology of Pig Iodine Deficiency(Local Thyroidsm or Goitrous Disease)

本研究应用病理组织学方法，对５５例缺碘地区猪的甲状腺组织进行研究，检出率为７５％～１００％，病理学表现为甲状腺上皮组织广泛、弥漫性增生、肥大和新腺泡的形成，显示碘的吸收不足。上皮细胞的反复增生、胶质储积，后期发生结节性甲状腺肿．甲状腺上皮弥漫性增生、肥大和新腺泡形成引起甲状腺肿大，而后期的结节性甲状腺肿则引起腺体不规则的缩小和表面的凸凹不平。

Using pathohistological methods, the research on pig’ s thyroid tissue of 55samples has been conducted in an iodine deficiency area。 The results showed that duringthe iodine deficiency perio, the thyroidism(goiter) became prevalent. As the featureof the pathological changed, the epithelial tissue of thyroid expanded, proliferated andhypertrophied,and the new glandular bladder formed in order to increase theabsorption of iodine。Thus,the constant proliferation of epithelial cells and thecolloidal accumulation were the common pathological changes at first, then the nodulargoiter developed. So, the results showed that the expansive proliferation and thehypertrophy of epithelial tissue of thyroid, and the development of glandular bladderinduced the goiter, and the last stage nodular goiter induced an abnormal reduction ofthe gland and its convexoconcave surface。