同种异体肾移植45例报告

Allograft Renal Transplantention(45 Cases Report)

我院１９８３～１９９２年共施行肾移植４５例，应用常规免疫抑制剂３例，应用ＣＳＡ三联用药４２例，后者效果明显优于前者，急性排异率减少到４０％，症状减轻，逆转容易，感染率降至２１．４％，人肾一年存活率提高到９１．４％。本文报道１３例病人测定ＣＳＡ谷值的作用及应用心痛定是预防肾毒性的有效性。

Abstract45 consecutive cases of allograft transplantention was reported in our ho-spital from 1983 to 1992. 3 cases was used with routing immune inhibitor,42cases used CsA-AzA-Pred. Better result was seen in latter,the incidence ofacute rejection decreased to 40%with lighter symptom and easier recovery. Theincidence of infection decreased to 21.4%. The survival rate of recipient andgraft for one year rose to 91.4%and 80%. The blood content of CsA wasestimated in 13 cases( 3 pairs).The function of this test and the effectivenessof using nifidipine to prevert mephrotoxicity of CsA were discussed. Key wores Renal transplantention CsA Nephrotoxity