摘要
目的报告1例伴有t(9;12)(q22;p13)易位的急性髓细胞白血病M2a。方法患者骨髓细胞短期培养后按常规方法制备染色体,采用R显带技术进行染色体核型分析;以9 号和12 号整条染色体涂染探针对其进行染色体涂染检测。结果染色体核型和染色体涂染分析均证实该患者具有t(9;12)(q22;p13)克隆性染色体异常。结论t(9;12)(q22;p13)易位是急性髓细胞白血病M2a的一种新的临床遗传学类型。
Objective To report an acute myelocytic leukemia M_~2a patient with t(9;12)(q22;p13).Methods Chromosome specimens were prepared by short-term culture of bone marrow cells.Karyotype analysis was made by R banding technique.Chromosome painting was performed using whole chromosome probes 9 and 12.Results Conventional karyotype analysis revealed t(9;12)(q22;p13) in this patient.Chromosome painting analysis confirmed this result.Conclusion The translocation of (9;12)(q22;p13)was a novel subtype of acute myelocytic leukemia M_(2a) .
出处
《江苏医药》
CAS
CSCD
北大核心
2005年第4期268-269,F003,共3页
Jiangsu Medical Journal
