多发性肌炎合并间质性肺病17例分析

Analysis of 17 patients with interstitial lung disease in polymyositis

目的:通过对17例多发性肌炎合并间质性肺病患者临床资料的分析以探讨其临床特点。方法:采用回顾性研究方法。结果:多发性肌炎合并间质性肺病者发热、咳嗽咳痰及关节痛出现率高,血沉明显增快,血抗核抗体(ANA)及抗Jo-1抗体的检出率高,肺部有特殊影像学改变,激素及免疫抑制剂有效。有半数以间质性肺病为首发症状。结论:多发性肌炎合并间质性肺病有特殊的临床表现,治疗效果不差。

Objective:To explore the clinical features of interstitial lung disease associated with polymyositis. Methods: Report 17 cases out of 62 patients, and analyzed with review of literatures that clinical features, serum examinations and treatment of the disease. Result: In interstitial lung disease associated with polymyositis, fever, cough and arthralgia appear more frequent, erythrocyte sedimentation rate is elevated, the positive rate of ANA and anti Jo-1 test is high. Special changes can be seen in lung.