新生儿肠道双歧杆菌数量与其相关影响因素的探讨

The preliminary exploration of the relationship between the Bifidobacterium in neonatal intestines and its relative factors

目的 探讨影响新生儿肠道双歧杆菌数量的相关因素。方法 以重庆医科大学附属二院和重庆市妇幼保健院的12 0例新生儿为研究对象,每例生后5～7d,均采集新鲜大便做双歧杆菌定量培养,并做10个相关因素的准确登记。结果 母亲分娩方式、临产期及产后是否使用抗生素、母亲妊娠期饮食习惯以及新生儿黄疸期长短与新生儿肠道双歧杆菌数量有相关性( P均<0 .0 1)。结论 提倡阴道分娩、临产期及产后不用抗生素、妊娠期多食发酵制品和素食,并尽量设法缩短新生儿黄疸时间。

Objective To explore the relative factors affecting the Bifidobacterium in neonatal intestines. Methods The Bifidobacterium from the cultured feces were counted in every neonates. The relationship between the Bifidobacterium in neonatal intestines and its relative factors was analyzed. Results The Bifidobacterium in neonatal intestines was related to mode of delivery, maternal administration with antibiotic or not (before and after delivery), dietary habit of the mother, and the duration of neonatal jaundice ( P <0.01). Conclusions Admini stration with antibiotic to their mothers should be avoided (before and after delivery). Fermented products and vegetable dish, vaginal delivery were encouraged. The duration of neonatal jaundice should be shortened. They were beneficial to sufficient Bifidobacterium in neonatal intestines.