164株阴沟肠杆菌的药物敏感性分析

Drug sensitivity analysis of the 164 strains of Enterobacter cloacae

目的 了解阴沟肠杆菌的药物敏感性情况以指导临床合理用药。方法 对中山大学附属第一医院近3年分离出的阴沟肠杆菌的标本分布及耐药情况进行回顾性分析。结果 共分离出16 4株阴沟肠杆菌,其对亚胺培南、头孢吡肟、阿米卡星和氧氟沙星的敏感性较高。结论 阴沟肠杆菌对3代头孢菌素耐药严重,呈多重耐药性。

Objective To investigate the drug sensitivity situation of Enterobacter cloacae to instruct application of the antibiotics reasonably.Method Retrospective analysis of the drug resistance situation and specimen distribution was made to the Enterobacter cloacae isolated from our hospital in the recent 3 years.Result Totally 164 strains of Enterobacter cloacae were isolated and were more sensitive to imipenem,cefepime,amikacin,ofloxacin.Conclusion Enterobacter cloacae was severely resistant to third generation cepholosporins and represented multiple drug resistance,imipenem remains to be the first choice to treat the severe infection which caused by Enterobacter cloacae .