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乙型肝炎前S1抗原、HBeAg与HBV-DNA的关系及临床意义 被引量:4

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摘要 目的 了解乙肝前S1抗原、HBeAg与HBV DNA之间的关系及临床意义。方法 用ELISA法检测乙肝前S1抗原、HBeAg ,荧光定量PCR检测HBV DNA。结果 HBeAg与HBV DNA的符合率为79.3 8% ,前S1抗原与HBV DNA、HBeAg一致率分别为74.74%、73 .71% ;115份HBV DNA阳性血清中,有3 3份(2 8.70 % )前S1抗原为阴性,有3 9份(3 3 .91% )HBeAg为阴性;79份HBV DNA阴性血清中,1份血清(1.2 7% )HBeAg阳性,16份标本(2 0 .2 5 % )前S1抗原阳性。结论 HBV DNA、HBeAg、乙型前S1抗原有较好的一致性,都可作为乙肝病毒存在和复制的指标。但三者的检出并不完全相同,提示他们所表达的意义并不完全一致,各自具有独立的临床意义。
机构地区 达州市中心医院
出处 《四川医学》 CAS 2005年第4期453-454,共2页 Sichuan Medical Journal
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参考文献5

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