2-对硝基苯基-5-芳基-1,3,4-噁二唑的合成与表征

Synthesis and Characterization of 2-p-Nitrophenyl-5-aryl-1,3,4-oxadiazoles

以自制的N,N′-二酰基肼在POCl3作用下脱水环化,合成了8个2-对硝基苯基-5-芳基-1,3,4-噁二唑类1化合物。其结构经1HNMR,IR,MS和元素分析表征,并对其裂解途径进行了探讨。

Eight novel 2-p-nitrophenyl-5-aryl-1,3,4-oxadiazoles were synthesized by cyclization of POCl 3 with N,N′-diacylhydrazines. The structures were characterized by 1H NMR, IR, MS and elemental analysis and the fragmentation mechanism of MS spectra was discussed.