转染内皮抑素基因联合放射治疗对肝癌移植瘤生长的影响
被引量：1
Inhibition of liver tumor growth by combining endostatin gene delivery with radiotherapy
摘要
实体瘤的生长和转移依赖于血管生成.用抗血管生成剂靶向肿瘤血管生成是新的肿瘤治疗方法之一.观察转染内皮抑素基因联合放射治疗对人肝癌BEL7402细胞株裸鼠移植瘤生长的影响,以探索内皮抑素联合放射治疗对肿瘤的治疗作用.
出处
《中华肝脏病杂志》
CAS
CSCD
北大核心
2005年第4期309-310,共2页
Chinese Journal of Hepatology
参考文献3
-
1Siemann DW, Shi W. Targeting the tumor blood vessel network to enhance the efficacy of radiation therapy. Semin Radiat Oncol, 2003, 13: 53-61.
-
2Hanna NN, Seetharam S, Mauceri HJ, et al. Antitumor interaction of short-course endostatin and ionizing radiation. Cancer J, 2000, 6:287-293.
-
3Shi W, Teschendorf C, Muzyczka N, et al. Gene therapy delivery of endostatin enhances the treatment efficacy of radiation. Radiother Oncol, 2003, 66: 1-9.
同被引文献10
-
1Mellon MJ, Ahn M, Jimenez JA, et al. Anti-angiogenic gene therapy for metastatic renal cell carcinoma produces tumor growth suppression in an athymic nude mouse model. J Urol, 2008, 179: 737-742.
-
2Brideau G, Makinen M J, Elamaa H, et al. Endostatin overexpression inhibits lymphangiogenesis and lymph node metastasis in mice. Cancer Res, 2007, 67:11528-11535.
-
3Zhang X, Xu J, Lawler J, et al. Adeno-associated virus-mediated antiangiogenic gene therapy with thrombospondin-1 type 1 repeats and endostatin. Clin Cancer Res, 2007, 13: 3968-3976.
-
4Tabruyn SP, Griffioen AW. Molecular pathways of angiogenesis inhibition. Biochem Biophys Res Commun, 2007, 355: 1-5.
-
5Ek ET, Dass CR, Choong PF. PEDF: a potential molecular therapeutic target with multiple anti-cancer activities. Trends Mol Med, 2006, 12: 497-502.
-
6Guan M, Jiang H, Xu C, et al. Adenovirus-mediated PEDF expression inhibits prostate cancer cell growth and results in augmented expression of PAI-2. Cancer Biol Ther, 2007, 6: 419-425.
-
7Hanawa H, Persons DA, Nienhuis AW. Mobilization and mechanism of transcription of integrated self-inactivating lentiviral vectors. J Virol, 2005, 79: 8410-8421.
-
8Dawson DW, Volpert OV, Gillis P, et al. Pigment epithelium-derived factor: a potent inhibitor of angiogenesis. Science, 1999, 285: 245-248.
-
9Fernandez-Garcia NI, Volpert OV, Jimenez B. Pigment epitheliumderived factor as a multifunctional antitumor factor. J Mol Med, 2007, 85: 15-22.
-
10Filleur S, Volz K, Nelius T, et al. Two functional epitopes of pigment epithelial-derived factor block angiogenesis and induce differentiation in prostate cancer. Cancer Res, 2005, 65:5144-5152.
-
1彭承宏,刘宏,刘颖斌,吴育连,王涌,赵之明,韩宝山.腺相关病毒介导的人内皮抑素基因转染对肝细胞性肝癌生长的抑制作用[J].实用肿瘤杂志,2005,20(2):111-114. 被引量：1
-
2谭亚琴,张文慧,云文秀,阎志虹.沙利度胺联合FOLFOX4方案治疗晚期胃癌22例疗效观察[J].中国煤炭工业医学杂志,2009,12(5):749-750. 被引量：1
-
3尹嘉,袁绍纪,张荣伟,卢培刚,骆纯,楼美清,卢亦成.转染内皮抑素基因对血管内皮细胞增殖的影响[J].医学综述,2007,13(23):1839-1840. 被引量：1
-
4谢雨婷,陈平.非小细胞肺癌的联合靶向治疗[J].国际呼吸杂志,2009,29(2):125-128.
-
5戚晓军,姜宇东.沙利度胺在肝动脉化疗栓塞中的作用[J].中华肿瘤防治杂志,2007,14(10):788-789. 被引量：8
-
6张迪,戈伟.肿瘤分子靶向治疗进展[J].武汉大学学报（医学版）,2011,32(5):705-708. 被引量：4
-
7潘琼,任凯,崇殿龙,张智瑞,周灿,刘浩,赵素容.3-溴丙酮酸对肝癌Bel7402细胞凋亡及相关蛋白表达的影响[J].蚌埠医学院学报,2016,41(9):1129-1131.
-
8徐复国,马清涌,郭坤,胡恒通,张珉,沙焕臣,宫晓光.Cyclopamine联合YH-16对人胰腺癌BxPC-3细胞的抑制作用[J].西安交通大学学报（医学版）,2010,31(3):283-287. 被引量：2
-
9邵俊伟,刘然义,易继林,卢绮萍,黄文林.内皮抑素转基因治疗裸鼠人肝癌的实验研究[J].中国普外基础与临床杂志,2006,13(2):145-149. 被引量：1
-
10陈斌,陈余清,蔡映云.抗血管生成治疗肿瘤研究的进展[J].国外医学（内科学分册）,2006,33(7):290-294. 被引量：7
