期刊文献+

转染内皮抑素基因联合放射治疗对肝癌移植瘤生长的影响 被引量:1

Inhibition of liver tumor growth by combining endostatin gene delivery with radiotherapy
原文传递
导出
摘要 实体瘤的生长和转移依赖于血管生成.用抗血管生成剂靶向肿瘤血管生成是新的肿瘤治疗方法之一.观察转染内皮抑素基因联合放射治疗对人肝癌BEL7402细胞株裸鼠移植瘤生长的影响,以探索内皮抑素联合放射治疗对肿瘤的治疗作用.
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2005年第4期309-310,共2页 Chinese Journal of Hepatology
关键词 转染内皮抑素基因 联合放射治疗 肝癌 移植瘤生长 Carcinoma,hepatocellular Radiotherapy Endostatin
  • 相关文献

参考文献3

  • 1Siemann DW, Shi W. Targeting the tumor blood vessel network to enhance the efficacy of radiation therapy. Semin Radiat Oncol, 2003, 13: 53-61.
  • 2Hanna NN, Seetharam S, Mauceri HJ, et al. Antitumor interaction of short-course endostatin and ionizing radiation. Cancer J, 2000, 6:287-293.
  • 3Shi W, Teschendorf C, Muzyczka N, et al. Gene therapy delivery of endostatin enhances the treatment efficacy of radiation. Radiother Oncol, 2003, 66: 1-9.

同被引文献10

  • 1Mellon MJ, Ahn M, Jimenez JA, et al. Anti-angiogenic gene therapy for metastatic renal cell carcinoma produces tumor growth suppression in an athymic nude mouse model. J Urol, 2008, 179: 737-742.
  • 2Brideau G, Makinen M J, Elamaa H, et al. Endostatin overexpression inhibits lymphangiogenesis and lymph node metastasis in mice. Cancer Res, 2007, 67:11528-11535.
  • 3Zhang X, Xu J, Lawler J, et al. Adeno-associated virus-mediated antiangiogenic gene therapy with thrombospondin-1 type 1 repeats and endostatin. Clin Cancer Res, 2007, 13: 3968-3976.
  • 4Tabruyn SP, Griffioen AW. Molecular pathways of angiogenesis inhibition. Biochem Biophys Res Commun, 2007, 355: 1-5.
  • 5Ek ET, Dass CR, Choong PF. PEDF: a potential molecular therapeutic target with multiple anti-cancer activities. Trends Mol Med, 2006, 12: 497-502.
  • 6Guan M, Jiang H, Xu C, et al. Adenovirus-mediated PEDF expression inhibits prostate cancer cell growth and results in augmented expression of PAI-2. Cancer Biol Ther, 2007, 6: 419-425.
  • 7Hanawa H, Persons DA, Nienhuis AW. Mobilization and mechanism of transcription of integrated self-inactivating lentiviral vectors. J Virol, 2005, 79: 8410-8421.
  • 8Dawson DW, Volpert OV, Gillis P, et al. Pigment epithelium-derived factor: a potent inhibitor of angiogenesis. Science, 1999, 285: 245-248.
  • 9Fernandez-Garcia NI, Volpert OV, Jimenez B. Pigment epitheliumderived factor as a multifunctional antitumor factor. J Mol Med, 2007, 85: 15-22.
  • 10Filleur S, Volz K, Nelius T, et al. Two functional epitopes of pigment epithelial-derived factor block angiogenesis and induce differentiation in prostate cancer. Cancer Res, 2005, 65:5144-5152.

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部