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CD20 CD45RA和溶菌酶在颜面粟粒性狼疮中的检测 被引量：3

Detection of CD20,CD45RA and LZM In Lupus Miliaris Faciei
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摘要 目的进一步探讨颜面粟粒性狼疮(LMF)的发病机理。方法采用免疫组化SP法对32例LMF患者皮损中CD20,CD45RA和溶菌酶进行检测。结果CD20,CD45RA和溶菌酶在颜面粟粒性狼疮中的表达明显高于正常对照组。结论在本病的发生发展中,T细胞介导的细胞免疫占有主导地位;B细胞可能仅作为抗原递呈细胞参与了本病的发病过程;溶菌酶亦起着主要作用。 Objective To research the pathogenesis of lupus miliaris faciei further. Methods The detection of CD20,CD45RA and LZM in 32 patients’ lesions were studied by histostain-SP method in immunohistochemistry.Results The detection of CD20,CD45RA and LZM in LMF were higher than that of normal tissues of faciei.Conclusion In the occurrence and development of this disease,T cell mediated cytoimmunity play a main role;B cell may participate in the pathogenetic progresss merely as antigen submission cells;LZM is also an important factor.
作者 郑凤兰 雷明君 赵宝亭 高顺强 林元珠
机构地区 河北医科大学第四医院皮肤科 河北医科大学中医院皮肤科
出处 《中国皮肤性病学杂志》 CAS 北大核心 2005年第4期203-205,共3页 The Chinese Journal of Dermatovenereology
关键词 颜面粟粒性狼疮 CD20 CD45RA 溶菌酶 免疫组化 Lupus miliaris faciei CD20 CD45RA LZM Immunohisto-chemistry
分类号 R529.4 [医药卫生—内科学]
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参考文献4

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同被引文献30

  • 1苗国英,郑凤兰,胡亚红,张西克,高顺强.氨苯砜联合转移因子治疗颜面粟粒性狼疮20例[J].临床皮肤科杂志,2005,34(1):51-51. 被引量：3
  • 2黄文阁,明玉华,刘丽丽,王敏进.中西医结合治疗面部播散性粟粒性狼疮疗效观察[J].中国皮肤性病学杂志,2006,20(3):186-186. 被引量：1
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  • 6DaroutiM,Zaher H. Lupusmiliaris disseminatus faciei pathologic study of early, fully developed ,and late lesions [J]. Int J Dermato1,1993,32 (7) :508-511.
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中国皮肤性病学杂志
2005年 第4期

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