摘要
目的:研究激肽释放酶激肽系统在成年大鼠阴茎海绵体的表达。方法:利用逆转录聚合酶链反应(RTPCR)技术分别检测SD大鼠阴茎和心脏组织中组织型激肽释放酶Ⅰ和激肽B2型受体mRNA的表达情况。结果:大鼠心脏与阴茎海绵体组织中均表达组织型激肽释放酶Ⅰ和激肽B2型受体mRNA,两者有几乎相同的表达水平,差异无显著性(P>0.05)。结论:在生理状态下,激肽释放酶激肽系统存在于阴茎海绵体组织中,而且与心血管系统的表达水平相当。
Objective: To study the expression of the kallikreins-kinins system in the corpus cavernosum of rats. Methods: The expression of tissue kallikrein Ⅰand kinin B2 receptor gene in the corpus cavernosum and heart of adult rats was detected by reverse transcription polymerase chain reaction (RT-PCR). Results: The tissue kallikrein Ⅰ and kinin B2 receptor were detected in the corpus cavernosum as well as in the heart of the rats and the contents were similar. Conclusion: A kallikreins-kinins system exists in the corpus cavernosum of rats, and the content is rich, almost similar to that in the heart. Natl J Androl,2005,11(4):278-280
出处
《中华男科学杂志》
CAS
CSCD
2005年第4期278-280,共3页
National Journal of Andrology
