摘要
目的:探讨M R动态增强对孤立性肺结节的鉴别诊断价值.材料和方法:对83例孤立性肺结节行M R动态增强,绘制MR动态增强时间-信号强度曲线,测量病灶的强化峰值(PH)、最大线性强化斜率(SS)、最大强化率(Emax)及1、2、3、4、5、6min时的信号强化率(E1、E2、E3、E4、E5、E6).结果:恶性结节及炎性结节的强化程度明显高于良性结节,恶性结节及炎性结节的PH、SS、Emax、E1～E6均明显高于良性结节(P＜0.01).恶性结节与炎性结节均强化明显,但两者之间的PH、SS、Emax、E1～E6无明显差异(P＞0.05).结论:MR动态增强能反映孤立性肺结节的血流动力学信息,对良、恶性结节的鉴别诊断有较高的临床应用价值.
Purpose:This study is to evaluate the efficacy of contrast enhanced dynamic MRI in differentiating solitary pulmonary nodules(SPNs).Materials and Methods:A prospective study was undertaken in83patients with SPNs using contrast enhanced dynamic MRI.Patterns of time-signal intensity curve(T-SI Curve)were made.Peak height(PH),steepest slope(SS),maximum enhancement(E max )and the en-hancement rates of signal intensity at the first(E 1 ),second(E 2 ),third(E 3 ),fourth(E 4 ),fifth(E 5 ),sixth(E 6 )minutes of T-SI curve were calculated.Results:Malignant nodules and inflammatory nodules enhanced significantly more than benign nodules,malignant nodules and inflammatory nodules showed obviously higher PH,SS,E max ,E 1 ～E 6 values than that of benign nodules(P<0.01).Malignant nodules and in-flammatory nodules enhanced obviously,but there was no significant differences in PH,SS,Emax,E 1 ～E 6 values between malignant nodules and inflammatory nodules(P>0.05).Conclusion:Contrast enhanced dynamic MR imaging can provide SPNs'hemodynamic information and is proved to be a valuable diag-nostic methods for differentiating SPNs.
出处
《中国医学计算机成像杂志》
CSCD
2005年第2期95-99,共5页
Chinese Computed Medical Imaging
