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激光诱导间质肿瘤热疗中激光能量在生物组织内传输规律的分析 被引量:9

Energy Distribution Analysis of Laser Transport in Biological Tissue for Laser-Induced Interstitial Thermotherapy
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摘要 采用蒙特卡罗模拟方法数值求解了不同波长(1064 nm和850 nm)时的激光诱导间质肿瘤热疗(LITT)中激光能量分别在人体的肝组织和前列腺组织内的传输,分析了影响激光能量空间分布的主要因素。穿透深度是影响激光能量在半径方向上分布区域的重要参数;在轴线方向上,穿透深度和激光加入头有效发射长度都对激光能量分布区域的大小有重要影响。 A Monte Carlo model was developed to simulate laser energy transport in biological tissues photon-number-independently and mesh-independently for laser-induced interstitial thermotherapy (LITT). In addition, laser transport characters in human liver tissue and prostate tissue at 1064 nm and 850 nm as well as its main influential factors were analyzed based on the present model. The numerical results showed that the energy deposition depended paramountly on penetration depth in radial direction and on both penetration depth and active emission length in axial direction.
出处 《中国激光》 EI CAS CSCD 北大核心 2005年第4期581-584,共4页 Chinese Journal of Lasers
基金 国家自然科学基金(50276032)资助项目。
关键词 医用光学和生物技术 肿瘤热疗 激光诱导间质肿瘤热疗 蒙特卡罗模拟 激光能量传输 Hyperthermia therapy Laser surgery Monte Carlo methods Tumors
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