血清C-反应蛋白水平在急性心肌梗死中的意义

Clinical significance of serum C-reactive protein in acute myocardial infarction

目的观察血清C反应蛋白(CRP)水平与急性心肌梗死(AMI)的关系。方法对急性心肌梗死(AMI)患者定量检测血清C反应蛋白(CRP)、心肌肌钙蛋白(cTnI)、肌酸激酶同工酶MB(CK MB)和肌红蛋白(Mb)水平,并对结果进行t检验分析。结果急性心肌梗死(AMI)患者血清C反应蛋白(CRP)、心肌肌钙蛋白(cTnI)、肌红蛋白(Mb)和肌酸激酶同工酶MB(CK MB)水平出现明显升高,与对照组比较差异显著(P<0.01)。结论血清中CRP是AMI诊断与治疗的敏感指标,血清CRP与cTnI、Mb、CK MB同时检测对AMI快速诊断、治疗和预后具有重要临床价值。

Objective To investigate the relation between serum C-reactive protein concentration and acute myocardial infarction. Methods The serum C-reactive protein (CRP),casdiac troponin I(cTnI),myoglobin (Mb) and creatine kinase isoenzyme (CK-MB) of the patients with acute myocardial infarction were measured.The differences between the AMI group and the control group were studied by T test. Results The serum CRP?TnI?Mb?CK-MB levels in AMI group were significantly higher than in normal groups.The difference between the two groups was remarkable (P<0.01). Conclusion The result shows that the CRP is regarded as an sensitive index in AMI.The caanges of the serum CRP?cTnI and Mb with AMI have clinical significance in diagnosis, cure and preditation.