柔嫩艾美耳球虫交叉抗药性试验

Cross Resistance of Eimeria tenella

以雏鸡为试验对象,以抗球虫指数(ACI)为判断指标,检测5 mg/kg马杜霉素,70 mg/kg盐霉素,1 mg/kg 地克珠利对抗盐霉素株、抗地克珠利株和实验室保存的敏感株的控制效果。结果表明,马杜霉素对3 个虫株都有很好的抑杀效果,地克珠利也可有效地控制抗盐霉素株,同时,盐霉素也可有效地控制抗地克珠利株,说明盐霉素和地克珠利2种药物之间没有交叉抗药性。

Chicken were used as experimental animals.The anticoccidial effects of 5 mg/kg maduramysin, 70 mg/kg salinomisin and 1 mg/kg diclazuril to salinomisin-resistant strain, diclazuril resistant strain, and sensitive strain were checked. The experiment demonstrated that maduramysin can control all of the three strain, diclazurol can contral salinomisin resistant strain, salinomisin can contral diclazuril resistant strain.There were no cross resistance between salinomisin and diclazuril.