23例乳腺派杰氏病诊治体会

Diagnosis and treatment of 23 cases Paget's disease

目的总结23例乳腺派杰氏(Paget's)病患者的诊断及治疗.方法收集我院自1984～2004年23例经病理确诊的乳腺Paget's病例,通过对病人的临床资料及治疗方法的分析,总结该病的诊治经验.结果乳腺Paget's病以慢性乳头皮肤改变为主要特点,钼靶X线多显示导管区恶性改变.细胞学检查见到Paget's细胞.术后7例失访,余16例随访时间最长13年,最短6月,其中3例出现术后远处转移.结论早期诊断及手术为主的综合治疗预后较佳.

Objective To summarize the experience of diagnosis and therapy by 23 patients with Paget's disease. Methods There are 23 patients with Paget's disease from 1984 to 2004,all the cases are definite by pathology.To summarize the experience of diagnosis and therapy though the patient's clinical date and healing way.Results The clinical characteristic of the disease is slow change of eczematoid.X ray often designs the changes of carcinoma ductal area.Paget's cell can be found by cytopathology.There are 7 cases lose visit,the longest visit time is 13 years,the shortest is 6 month,3 cases have distant place transfusion.Conclusions Prolonged survival can be achieved in early diagnosis and combination treatment with surgery as the major treatmentmodality.