摘要
本实验用推挽灌流技术结合高效波相──电化学测定方法，从突触前递质释放的角度对大鼠外测网状旁巨细胞核（RPGL）去甲肾上腺素（NE）在针刺镇痛中的作用进行了研究。从结果看出针后病阈升高越明显的动物，其RPGL中NE释放减少也越明显，两者呈负相关，说明RPGL中NE释放减少与针刺镇痛密切相关。
Norepinephrine(NE) of the nucleus reticularis paragigantocellularis lateralis(RPGL) plays an important role in acupuncture analgesia(AA). The aim of this experiment was to investigate the role of NE in RPGL during AA at presynaptic level by using push-pull perfusion, high performance liquid chromatography with electrochemical detection (HPLC-ECD) techniques.The results indicated that pain thresholdold increased significantly after 20 min of EA, while the content of NE and its metabolite MHPG in the perfusate from the RPGL was markedly decreased. A negative correlation existed between the changes of pain threshold and the release of NE and MHPG.It is indicated that electroacupuncture (EA) is able to inhibit the release of NE from the RPGL during AA
出处
《针刺研究》
CAS
CSCD
1994年第1期20-25,共6页
Acupuncture Research
