以体温作为治疗有机磷中毒用药指征的分析

Analysis on Medication by Temperature in the Therapy of Acute Organophosphorus Insecticides Poisoning

目的 探讨并研究以体温作为衡量阿托品治疗急性有机鳞中毒用药指征的优越性。方法 将我科近两年收治的中毒前无严重心肺疾患的急性有机磷中毒212例作为分析对象,随机分为两组:一组以阿托品化出现与否作为阿托品用药日程中停药与减量的指征(A组),另一组以体温作为阿托品用药的指征(B组)。价治愈率、死亡率和住院时间。结果 (1)治愈率:B组高于A组;(2)住院时间:B组住院时间少于A组;(3)阿托品中毒:B组明显低于A组;(4)农药中毒反跳:B组出现机会少于A组。结论 以体温作为阿托品治疗急性有机磷中毒过程中用药的指征与传统方法相比具有显著优越性,阿托品中毒及多种并发症出现机会明显减少,住院时间也缩短,可视为治疗急性有机磷中毒的理想方案。

Objective To analysis the advantage of the medication of atropine by temperature in the therapy of acute organophosphorus insecticides Poisoning.Methods 212 subjects,inclusion criteria were that they did not have severe disease of heart,lung, liver or kidney before poisoning in the past two years .The 212 subjects were randomly assigned to two groups:106 cases belonged to traditional group (group A) that taking atropine by atropinogene, while the improved regiman group (group B) taking atropine by temperature. The cure rate, mortality and the hospitalization days were compared in each group.Results (1)The cure rate in group B was higher than that of group A;(2)The hospitali zation days in group B was lower than that of group A;(3)The incidence of atropine poisoning in group B was less than group A;(4)The rebound of pesticide poisoning in group B was less than group A.Conclusion Compared to conventional method, it's effect is more dorminant to injecting atropine by temperature,the incidence of atropine poisoning and the rebound of pesticide poisoning was dominantly decreased,and can be considered the safetest and most reliable program in the treatmant of acute organophosphorus insecticides poisoning.