超临界CO_2萃取改进助孕3号丸提取工艺及药效学评价

Study on Extraction of Zhuyun 3# by Supercritical CO2

本文利用超临界CO2 萃取技术改进助孕3号丸提取工艺。分别采用了四种超临界CO2 萃取工艺,以药效实验和总黄酮含量为评价指标,并与原制剂工艺比较,比较了五种工艺的优劣。助孕3号丸的最佳提取工艺条件为女贞子、白术、续断三味药经SFE萃取后,药渣再水提,另外黄芪等五味药材水提。

To optimize the extraction process for Zhuyun 3# pill by supercritical CO_2.Five kinds of supercritical CO_2 extraction method had been applied.The methods were estimated by the pharmacological results and the content of flovone.The best extraction process for Zhuyun 3# pill was that Lüzhenzi, Baizhu and Xuduan were extracted with supercritical CO_2 and the residue was estracted by water, the other five kinds of medicinal materials were extracted by water.