摘要
报道了一种非光气法合成除草剂吡嘧磺隆中间体5 [ (甲氧羰基)氨基磺酰基] 1 甲基吡唑4 羧酸乙酯(简称吡唑磺酰氨基甲酸酯)的新方法,由碳酸二甲酯与5 氨基磺酰基1 甲基吡唑4 羧酸乙酯(简称吡唑磺酰胺)在甲醇钠存在下反应制得产品, 收率85%。产品的结构经元素分析、IR、1HNMR等证实, 并对反应进行的可能机理进行了探讨。结果表明新方法具有反应条件温和、操作安全、简便、收率高的优点。
A new method of synthesis of ethyl 5-[(methoxycarbonyl)aminosulfonyl]-1-methy-pyrazole-4-carboxylate was reported.Using ethyl 5-aminosulfonyl-1-methyl-pyrazole-4-carboxylate and dimethyl carbonate as starting materials.The yield is 85%.The product was confirmed by elemental analysis,IR and 1H NMR.The possible (mechanism) of reaction was discussed.The results show that this new method has many advantages,such as moderate (reaction),the easy and safety operate conditions and high yield.
出处
《化学工程》
EI
CAS
CSCD
北大核心
2005年第2期69-70,73,共3页
Chemical Engineering(China)
基金
陕西省自然科学基金项目 (2001H11)
陕西省火炬计划 (00KH42)资助项目
关键词
非光气法
吡嘧磺隆
中间体
碳酸二甲酯
non-phosgene
pyrazolsulfuron-ethyl
intermediate
dimethylacrbonate