子宫动脉栓塞治疗子宫腺肌病45例疗效分析

Treatment of Adenomyosis by Uterine Arterial Embolization: Report of 45 Cases

目的:探讨子宫动脉栓塞术(UAE)治疗子宫腺肌病的临床疗效。方法:对4 5例子宫腺肌病的患者行UAE治疗,术后观察患者经期、经量、痛经程度、子宫体积、贫血情况和血清CA12 5变化。结果:术后6个月月经周期、经期、经量均正常,术后12个月痛经完全缓解39例,5例明显缓解,1例部分缓解;子宫体积平均缩小4 1.3% ;术后血清CA12 5迅速下降至正常或接近正常,术后1个月平均降低78.0 5 % ,治疗前后比较差异有非常显著性(P <0 .0 0 1)。结论:UAE治疗子宫腺肌病近期临床疗效显著,安全性好,患者接受程度高。

Objective:To assess the clinical effects of uterine arterial embol ization(UAE) on adenomyosis.Methods:The 5.0F cobra or 3.0 FASTRCKER-325 was placed into the double uterine arteries which be then injected particulate KM G embolization for treatment of adenomyosis in 45 patients. In the 1st?2nd?3rd ?6th?9th and 12th month after the operation, menstrual volume and duration, degree of dysmenorrhea, uterine volume, anemia, and serum CA 125 levels were investigated. Results:The menstrual cycle,duration,and volume retumed to normal after 6 month of thera py.After UAE, the complete re mission of dysmenorrhea was found in 39 patients, partial remission in 6 cases. The bodies of uterus reduced about 41.3% in average. The serum CA 125 levels declined rapidly to normal or close to normal in one month after treatment of UAE, there was asignificant difference compared to pre-operation (P<0.001). Conclusions: UAE is a safe, confirmed and satisfactory method for treatment of aden om yosis.