1Veloso M, WrbaF, Kaserer K, et al. p53 gene status and expression of p53, mdm2, and p21Wafl/Cip1 proteins in colorectal cancer [J]. Virchows Arch, 2000,437(3) :241.
2Quelle DE, Zindy F, Ashmun RA, et al. Alternative reading frames of the INK4a tumor suppressor gene encode tow unrelated proteins capable of inducing cell cycle arrest[J]. Cell, 1995 ,83 :993.
3Serrano M. A new regulatory motif in cell - cycle control causing specific inhibition of cyclin D/CDK4 [J]. Nature, 1993, 366(6456) :704.
4Haber DA. Splicing into senescence: the curious case of p16 and p19ARF[J]. Cell, 1997,91: 555.
5Shapiro G, Edward C, Kobzik L, et al, Reciprocal Rb inactivation and p16INK4a expression in primary lung cancers and cell lines[J].Cancer Res, 1995,55:505.
6Kamijo T, Zindy F, Roussel M, et al. Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF[J]. Cell, 1997,91:649.
7Esteller M, Cordon - Cardo C, Corn PG, et al. p14ARF silencing by promoter hypermethylation mediatesabnormal intracellular localization of MDM2[J]. Cancer Res, 2001,61 (7) :2816.
8Kurokawa K, Tanaka T, Karo J. pl9ARF prevents G1 cyclin - dependent kinase activation by interacting with MDM2 and activating p53 in mouse fibroblasts[J]. Oncogene, 1999, 18:2718.
9Magdinier F, Wolffe AP. Selective association of the methyl - CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia[ J]. Proc Natl Acad Sci USA, 2001,98(9) :4990.
10Pomerantz J, Schreiber N, Linjeois N, et al. The INK4a tumor supopressor gene product, p14ARF interacts with MDM2 and neutralizes MDM2s inhibition ofp53[J]. Cell, 1998, 92:713.