踝臂指数与冠状动脉病变严重性的关系研究

The Relationship between Ankle-branchial index and Severity of Coronary Heart Disease.

目的 探讨踝臂指数(ABI)与冠状动脉病变程度的关系。方法 选择性冠状动脉造影患者5 2例分为冠心病组和正常组(对照组) ,其中冠心病组(依据主要分支狭窄≥70 %的患者做leaman冠状动脉记分,将冠状动脉记分≤6分与>6分的两组,将各组患者的ABI进行对比研究,并将冠心病组中的冠状动脉记分与患者的ABI进行直线相关分析。结果 正常组与冠心病组ABI比较(P <0. 0 .0 1)、冠心病组中冠脉记分≤6分与>6分两组患者ABI比较(P <0 . 0 5 ) ,冠脉单支病变与多支病变患者ABI比较(P <0 . 0 0 1) ,均具有显著性差异,冠脉病变记分与ABI呈显著性负相关(r=- 0 . 4 5 ,P <0 . 0 5 )。结论 踝臂指数与冠心病发生,发展密切相关,有助于预测冠状劲脉病变程度。

Objective To explore the relationship between ank le -branchial index (ABI) and severity of coronary heart disease. Methods 52 cases were divided into coronary heart disease (CHD) group (27 cases) and normal group (25 cases), according to the result of electronic coronary angi ography. According to the leaman coronary artery score >6 or ≤6, the patients in CHD group were divided into two subgroups. According to the number of coronar y atherosclerosis, patients in CHD group were also divided into simple and multi ple atherosclerosis subgroups. The ABI of patients between groups were compared. Results The ABI were significantly lower in CHD group(P<0 .001), leaman coronary artery score >6 subgroup (P<0.05) and multiple at herosclerosis subgroup (P<0.001) than in normal group, leaman coronary art ery score≤6 subgroup and simple atherosclerosis subgroup. Leaman coronary arter y score was significantly negative correlation to ABI(r=-0.45,P<0.05). Conclusions ABI is not only an important and independent predictiv e index of CHD, but also one of the predictive index as the extent of coronary a therosclerosis.