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高血压患者动态脉压与心肌重构的关系

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摘要 目的 探讨高血压患者动态脉压随年龄变化的趋势及其与左心室肥厚、左室舒张功能的关系。方法 将患者按年龄分为三组,比较不同年龄组的2 4h动态血压及心脏超声检查结果,分析其2 4h收缩压、舒张压、2 4h及白昼、夜间的平均脉压、左室心肌重量指数及左室舒张期充盈率。结果 Ⅰ组2 4h收缩压、舒张压、平均脉压呈轻度增高,LVMI无明显改变而左室舒张功能却已有下降(P <0 . 0 1) ;Ⅱ组2 4h收缩压与Ⅰ组比较有增高(P <0 . 0 5 ) ,2 4h舒张压、平均脉压与Ⅰ组较接近,LVMI与Ⅰ组比较明显增高,左室舒张功能与Ⅰ组比较明显降低(均P <0 . 0 1) ;Ⅲ组的2 4h收缩压与Ⅰ、Ⅱ组比较增高明显(P <0 .0 1) ,舒张压急剧下降,而脉压却急剧上升,LVMI与Ⅰ、Ⅱ组比较增高更明显,左室舒张功能与Ⅰ、Ⅱ组比较降低亦更明显(均P <0 . 0 1)。结论 高血压病患者随着年龄的增长,脉压呈加速升高趋势,脉压升高更易导致左室肥厚和左室舒张功能减退,动态脉压较诊所脉压与左室肥厚的相关性更强。
机构地区 浙江省人民医院
出处 《心脑血管病防治》 2005年第2期28-30,共3页 CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT
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