异丙酚与芬太尼、安定配伍应用于无痛人工流产的临床分析

Clinic analysis on co-appliance of propofol, fentanyl and diazepam in painless abortion

目的:比较研究早孕妇女行无痛人工流产时应用异丙酚、芬太尼和安定配伍与单独应用异丙酚的效果,为临床更好地开展无痛人工流产术提供麻醉学保障。方法:选择自愿实施无痛人工流产的妇女200例,将其随机分为两组:A组以安定3mg,芬太尼0.1mg静注,2min后缓慢静注异丙酚。B组直接静脉注射异丙酚。观察术中镇痛效果、宫口松弛度、异丙酚用量和手术时间。结果:结果表明A、B两组术中需追加异丙酚例数比较有明显的统计学差异(P<0.05);扩宫满意例数和术中镇痛满意例数有显著的统计学差异(P<0.01)。结论:异丙酚与芬太尼、安定配伍应用镇痛效果好,宫口松弛明显,手术时间短,异丙酚用量少。

Objectives To compare the effect of Propofol, fentanyl and diazepam co-appliance and the singleness appliance of propofol in the induced abortion on early stage of pregnancy, so as to provide the anaesthetic basis for the induced painless abortion in clinic practice. Method 200 women who wanted to have induced painless abortion were randomly divided into two groups: group A were first injected with 3mg of diazepam and 0.1mg of fentanyl, then injected with Propofol slowly two minutes later while group B were directly injected with propofol only. The antalgic effect , the uterus flabby degree , the dosage of propofol and the duration of operation were noted and analysed. Results There was significant difference between group A and B(P<0.05). The effect of antalgic, the uterus flabby degree were much better in group A than in group B, with shorter duration of operation and less dosage of Propofol. Conclusion The co-appliances of propofol, fentanyl and diazepam have a better effect, and are proposed to be used in the clinic practice of painless abortion.