胎儿器官组织和母血中常量元素研究

Study on macroelements in fetal organic tissues and mother serum

目的 探讨正常胎儿器官组织和母血中多种常量元素的水平、分布以及元素间的关系。方法 样品经HNO3 +H2 O2 微波消解系统消解后 ,用电感耦合等离子体发射光谱法 (ICP -AES) ,测定胎儿大脑、小脑、心脏、肝脏、肾脏、腓肠肌、胎盘以及母血中钠、钾、钙、镁、磷含量。结果 5种元素中钠、钾、磷在胎儿各器官组织中的含量较高 ;钙主要分布于胎儿腓肠肌和胎盘 ;镁则主要分布于胎儿心脏、肝脏和肾脏 ;相同组织中不同元素之间以及同一元素在不同的组织中均存在一定的相关性。结论 正常胎儿器官组织中常量元素的含量和分布具有一定的特征性和相关性。

Objective To study the contents, distributions and correlations of some macroelements in the organic tissues of healthy fetus and the maternal blood.Methods The samples from fetal cerebrum, cerebellum, heart, liver, kidney, gastrocnemius, placenta and mother serum were digested with nitric acid and hydrogen peroxide solution in microwave digestion system. Then the contents of sodium, potassium, calcium, magnesium and phosphorus in those sample solutions were determined by inductively coupled plasma atomic emission spectrometry.Results Among the five elements, sodium, potassium and phosphorus were abundant in all the above fetal tissues, calcium existed mainly in the fetal gastrocnemius and placenta, and magnesium existed mainly in the fetal heart, liver and kidney. Correlations between the contents of various elements in the same organ as well as the same element in different organs were observed in the study.Conclusion The contents and distributions of macroelements in the healthy fetal organisms presented remarkable characteristics and correlations.