摘要
昆虫病毒作为生物防治的一个重要方面而被日益广泛地使用。在自然环境中和在生产病毒制剂的过程中,人们与病毒的长期接触,昆虫病毒是否会感染人及哺乳动物,一直是国内外昆虫病毒研究人员的重要研究内容。1975年,联合国世界卫生组织在日内瓦召开的一次有关医学病毒学的讨论会上,将病毒杀虫剂的潜在生态危险列为一项课题。因此,多年来国内外学者做了大量的昆虫病毒的安全性试验,认为昆虫病毒对人、畜等哺乳动物以及家禽、植物等均安全。特别是颗粒体病毒的宿主专一性。
The experimental infection of mammals (such as mouse, golden hamster and nude mouse) was conducted with Pieris rapae Granulosis Virus (PrGV) of baculoviridae of insect virus by way of peritonal and intravenous injection, per os and inhalation. 7—50 days after injection, target insects were reinoculated with the visceral extracts of infected mammals and killed by 5—100%, displaying typical symptom infected by granulosis virus. GV and its latticed structure of inclusion body were found in the ultrathin section of spleen which took out from infected nude mouse via peritoneal injection under electronmicroscope.
出处
《微生物学报》
CAS
CSCD
北大核心
1989年第6期470-473,共4页
Acta Microbiologica Sinica
关键词
菜粉蝶病毒
哺乳动物
感染
Pieris rapae
Granulosis virus
Experimental infection
