摘要
【目的】探讨血清TPS和CA125与卵巢癌的关系,为卵巢癌的临床诊断、病情监测提供新方法。【方法】用ELISA法分别检测卵巢良性肿瘤和卵巢癌患者化疗前后血清TPS和CA125水平。【结果】卵巢癌患者血清TPS和CA125水平均较良性肿瘤患者高,差异有显著性(P<0. 01)。血清TPS和CA125诊断卵巢癌的敏感度和特异度无差别。卵巢癌患者2个疗程化疗后血清TPS和CA125水平显著下降(P<0. 01 )。【结论】血清TPS和CA125均可作为卵巢癌诊断、病情监测的临床指标,二者联合检测可提高其临床应用价值。
To explore the relationship of TPS and CA125 in ovarian cancer in order to determine their clinical significance in diagnosis and monitoring of ovarian cancer.Serum levels of TPS and CA125 were both detected by means of ELISA in patients with ovarian neoplasm and the variation of them before and after chemotherapy in patients treated as ovarian cancer.Both serum TPS and CA125 levels in carcinoma patients were significantly higher than those in benign patients( P <0.01) . Serum TPS and CA125 showed similar sensitivities and specificities in diagnosis of ovarian cancer and their levels both decreased significantly after 2 course of chemotherapy( P <0.01).[Conclusion]Serum TPS and CA125 are both useful in the diagnosis and monitoring of ovarian cancer. Their clinical value can increase in combined use of them.
出处
《医学临床研究》
CAS
2005年第4期440-442,共3页
Journal of Clinical Research
