阵发性室上性心动过速78例药物复律的临床观察

Clinical Observation of Drug Conversion on 78 Patients with Paroxysmal Supraventricular Tachycardia

目的探讨阵发性室上性心动过速最佳复律药物。方法78例101例次阵发性室是性心动过速患者,随机分成普罗帕酮、维拉帕米、三磷酸腺苷(ATP)、胺碘酮、毛花苷丙等五组治疗。结果阵发性室上性心动过速转律成功率普罗帕酮率93.8%、维拉帕米92%、三磷酸腺苷90%、胺碘酮71.4%、毛花苷丙60%。不良反应率普罗帕酮3.1%、维拉帕米12%、三磷酸腺苷75%、胺碘酮42.9%、毛花苷丙10%。结论普罗帕酮转复阵发性室上性心动过速成功率最高,不良反应最低,可作为临床转复阵发性室上性心动过速首选药物。

Objective To discuss the best drug used in the conversion of paroxysmal supraventricular tachycardia. Methods All the 78 patients with paroxysmal supraventricular tachycardia were divided into five groups at random, respectively administered with different drugs.Results Propafenone's success rate of conversion was 93.8%, which is the highest among the five drugs. Others' success rate were respectively 92.0% (verapamil), 90.0% (adenosine triphosphate), 71.4% (amiodarone) and 60.0% (Lanatoside C). Also, Propafenone's side reaction rate is 3.1%, lower than that of any other one.Conclusion Propafenone can act as the first choice drug, for its success rate is the highest while its side reaction rate is the lowest.