摘要
介绍了以2,4-二氯苯乙酮为原料通过催化溴化、缩合反应、与三氮唑钠反应制得原药,原药含量达到92%以上。并对合成条件进行了研究,取得了较为满意的结果。
Etaconazole was synthesized by catalysic brimination, condensation, reacting with sodium 1H-1,2,4-triazole 2,4-dichloroacetophenone. The purity was more than 92%. Some important reaction conditions were discussed and determined.
出处
《浙江化工》
CAS
2005年第4期20-21,35,共3页
Zhejiang Chemical Industry
基金
本项目系浙江省科技厅资助项目(2003C32012)
