以心肌酶显著增高为主的甲减性心脏病一例和文献回顾

Hypothyroid heart disease with increased myocardial enzymes—one case reportand literature review

甲减临床表现复杂,可引起甲减性心脏病、心肌酶增高,尤以肌酸激酶(CK)增高为主,易误诊为冠心病、心肌梗死。可能与甲状腺激素减少、黏蛋白和黏多糖沉积引起心肌黏液水肿有关。故血脂、CK异常增高而其余心肌酶无明显变化者应考虑甲减性心脏病,及时行甲状腺功能测定,以免误诊漏诊。

Some patients with primary hypothyroidism would suffer from hypothyroid heart disease with raised serum levels of myocardial enzymes, especially creatine phosphokinase (CK), and be easily mistaken as coronary heart disease and myocardial infarction.It can be relevant to the deposit of mucopolysaccharides and mucoproteins in the myocardium, leading to myocardial myxedema. So patients with hyperlipidemia, obviously high level of CK and without high levels of other myocardial enzymes should receive tests for thyroid functions in time to avoid mistaken diagnosis.