摘要
小鼠球后注射D-半乳糖80mg/kg,50d后造成亚急性衰老模型,同时口服天麻4、8g/kg能显著恢复D-半乳糖衰老模型小鼠被动回避反应能力的下降,明显提高RBC中SOD活力,皮肤羟脯氨酸含量,减少心肌脂褐质,对脑、肝脂褐质减少不明显。
A model of s bacute senility state was established in mice by successive retrobulbar injectiou of 80 mg/kg D-galactose for 50 days. Concomitant oral administration of 4 g/kg and 8 g/kg gastrodia can effectively recovcr the decreased ability of the passive avoid ance reaction in the model animals.The activity of RBC SOD and the contents of hydroxyproline in the animals skin were markedly increased as well as the lipofuscin of myocardium. However, gastrodia was less effective to lower lipofuscin in liver and brain.
出处
《中草药》
CAS
CSCD
北大核心
1994年第10期521-523,共3页
Chinese Traditional and Herbal Drugs