芍药提取物CY对豚鼠皮肤疱疹病毒感染的作用

Effect of CY[Extract of Common Peony (Paeonia lactiflora)]on the Inhibition of HSV-1 Skin Infections in Guinea Pigs

芍药提取物CY对单纯疱疹病毒Ⅰ型（HSV－1）感染所致豚鼠皮肤病损，有良好的治疗作用，用药后次日即可起效，尤为5mg／ml组作用强度与阳性对照药病毒唑十分相近，用药4d便可基本治愈，10mg／ml组和2．5mg／ml组也分别于药后第6或第7天痊愈，提示CY是一种有效的抗HSV－1药物。

CY (Extract of Paeonia lactiflora Pall. ) was found to have significant therapeutic effect ou skin lesions of HSY-1 infection in guinea pigs at 5mg/ml concentration. Inhibition effet on the development of skin lesions was similar to ribavirin, with recoyery 4 days after treatment. At 10 or 2.5mg/ml recovcry was also achieved after 6 or 7 days respectively. The results showed that CY is an effective anti-HSV-1 drug.