口腔原虫感染与口腔疾患关系的调查研究

Study of the Relationship between Oral Parasitic Protozoa Infection and Dental Diseases

目的了解福州市不同年龄段学生的口腔原虫感染情况以及与口腔疾患之间的关系,并探讨提高检出齿龈内阿米巴(Eg)的方法。方法采用locke液培养法与直接涂片法检测口腔原虫并进行比较,记录学生的牙龈出血与龋齿情况。结果学生的总感染率为57.58%,其中大学生的Eg感染率(71.15%)依次高于中专生(53.49%)、初中生(42.47%),小学生(39.13%)最低。用locke液培养Eg检出率(71.15%)明显较直接涂片法(44.87%)高(P<0.005)。牙龈出血和龋齿的口腔疾患者的口腔原虫感染率(80.62%)较口腔健康者(39.41%)高(P<0.005)。结论随着年龄增长口腔原虫感染增高,普查或个体检查时采用locke液培养法可提高检出率,口腔疾患的口腔原虫感染率较健康人群高,提示Eg感染在一定条件下可引起牙周病。

Objective To understand oral infection of protozoa in different age groups of students in Fuzhou city and its relationship to dental diseases as well as to explore methods of better detection rate of Entamoeba gingivalis(Eg).Method Total protozoa were recorded from direct smears and locke cultures with information on gingival bleeding and dental caries. Results Total infection rate was 57.58%, with a higher infection rate of Eg in university students (71.15%) than either in high school students(53.49%) or in middle school students(42.47%), and lowest in the primary school students(39.13%). Positive rate was significantly higher with locke culture method(71.15%) than with direct smear method(44.87%, P< 0.005). Oral parasitic protozoa infection rate in patients with gingival bleeding and dental caries (80.62%) was greater than in common healthy population(39.46%, P< 0.005). Conclusion Oral parasitic protozoa infection increases with age. Positive rate rose by the application of locke culture method in mass survey as well as in individual examination. The fact that Eg infection rate in patients with diseases in oral cavity was higher than in common population indicated that Eg infection can cause periodontal diseases under certain conditions.