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计算机辅助成像分析法在微丸圆整度评价中的应用 被引量：4

Evaluation of pellets sphericity using computer assistant image analysis
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摘要 目的建立计算机辅助的成像分析平台,分别考察市售的空白丸芯和自制的GBE微丸的圆整度。方法采用计算机辅助的成像分析法。结果空白丸芯和GBE微丸的纵横比(AR)值分别为1.16±0.09,1.14±0.09(n=25),形状因子(eR)值分别为0.56±0.12,0.62±0.14(n=25)。结论该方法能够直观、简便地评价微丸的圆整度,所制备的GBE微丸圆整度较好。 OBJECTIVE: To establish a computer assistant image system for investigating the pellets sphericity. METHODS: The computer assistant image analysis was applied. RESULTS: The aspect ratios of the blank and GBE pellets were 1.16 ± 0.09, 1.14 ± 0.09 (n = 25), and the shape factors (e R) were 0.56 ± 0.12, 0.62 ± 0.14 (n = 25). CONCLUSION: The pellets sphericity can be evaluated directly and conveniently by the computer assistant image analysis. The sphericity of GBE pellets was desirable.
作者 王俊 周寅 曹志娟 赖顺果 裴元英
机构地区 复旦大学药学院药剂学教研室 复旦大学药学院药物分析学教研室 复旦大学药学院药理学教研室
出处 《中国药学杂志》 EI CAS CSCD 北大核心 2005年第7期529-531,共3页 Chinese Pharmaceutical Journal
关键词 计算机辅助 成像分析 微丸 圆整度 Image analysis Spheres
分类号 R944 [医药卫生—药剂学]
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参考文献10

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二级参考文献4

共引文献32

同被引文献41

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引证文献4

二级引证文献14

中国药学杂志
2005年 第7期

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