渔区年轻人主动脉蛋白聚糖和嗜苏丹病变的定量分析

Proteoglycan Analysis and Morphometric Study on the Sudanophilic Lesions of Arterial Intima in Young Adults in Fishing Zone

本文对渔区３６例意外死亡的年轻人（１５～３９岁）新鲜（死后２４ｈ内）主动脉进行了蛋白聚糖和嗜苏丹病变定量分析，同时与以往报道的南宁和北京人主动脉的蛋白聚糖和嗜苏丹病变测定结果进行比较。结果是：①蛋白聚糖总量２１１４±５８４（μｇ糖醛酸／ｇ内中膜湿重，下同）；硫酸乙酰肝素－蛋白聚糖４８１±１２７，占蛋白聚糖总量的２３．１％，硫酸软骨素－蛋白聚糖１００４±３８６，占４６．７％；硫酸皮肤素－硫酸软骨素－蛋白聚糖６２８±１９５，占３０．２％；（２）主动脉内膜嗜苏丹病变测试结果明显好于南宁，更好于北京。

Proteoglycan analysis and morphometric study on the sudanophilic lesion of the aortas anatomizing in 24 hours) have been performed in 36young adults who died unexpected in fishing zone. The results were compared with that of Nanning and Peijing.The result shows that:(1)The total proteoglycan:2 113±584;heparan sulfate-proteoglycan: 81±127(23.1%);chondroitin sulfate-proteoglycan: 1 004±386(46.7%);Dermatan sulfate-chondroitin sulfate-proteoglycan:628±195 (30.2%).(2) The sudanophilic lesion of the aortic intima were obviously lighter than Nanning's and Peijing's.